Prothrombin Mutation G20210A as a Cause of Budd-Chiari Syndrome
نویسنده
چکیده
characterized by thrombus formation in the hepatic vein.1 Untreated, prognosis is generally poor. The main interventions are construction of an operative shunt and orthotopic liver transplantation.2 The prothrombin 20210 G to A mutation (G20210A) has been shown to cause spontaneous production of fibrin and an increased risk of thrombosis. This mutation may have caused cases of Budd-Chiari syndrome that previously were deemed idiopathic.3
منابع مشابه
Risk of Budd-Chiari Syndrome Associated with Factor V Leiden and G20210A Prothrombin Mutation: A Meta-Analysis
BACKGROUND Various studies have demonstrated that factor V Leiden (FVL) and G20210A prothrombin mutation contribute to the risk of Budd-Chiari syndrome (BCS), while other studies provided conflicting findings. In order to derive more precise estimations of the relationships, a meta-analysis was performed. METHODS Eligible articles were identified through search of databases including Pubmed, ...
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